Publications

Pubmed

Balaska, S. et al. Predictive chemoproteomics and functional validation reveal Coeae6g-mediated insecticide cross-resistance in the malaria vector Anopheles gambiae. Nat Commun 16, 10772, doi:10.1038/s41467-025-65827-4.

Kefi, M., et al., ABCH2 transporter mediates deltamethrin uptake and toxicity in the malaria vector Anopheles coluzzii. PLoS Pathog, 2023. 19(8): p. e1011226.

Vlogiannitis, S., et al., Reduced proinsecticide activation by cytochrome P450 confers coumaphos resistance in the major bee parasite Varroa destructor. Proc Natl Acad Sci U S A, 2021. 118(6).

Samantsidis, G.R., et al., 'What I cannot create, I do not understand': functionally validated synergism of metabolic and target site insecticide resistance. Proc Biol Sci, 2020. 287(1927): p. 20200838.

Ingham, V.A., et al., A sensory appendage protein protects malaria vectors from pyrethroids. Nature, 2020. 577(7790): p. 376-380.

Balaska, S. et al. Predictive chemoproteomics and functional validation reveal Coeae6g-mediated insecticide cross-resistance in the malaria vector Anopheles gambiae. Nat Commun 16, 10772, doi:10.1038/s41467-025-65827-4.

Wood, M.J., et al., Bacteria isolated from biodiverse Mediterranean island habitats yield a large array of biopesticidal metabolites against mosquito larvae. Appl Environ Microbiol, 2025: p. e0096625.

Vervaet, L., et al., Acaricide resistance mechanisms and host plant responses in the tomato specialist Aculops lycopersici. Pest Manag Sci, 2025. 81(2): p. 946-958.

Sarrassat, S., et al., High exposure to malaria vector bites despite high use of bednets in a setting of seasonal malaria in southwestern Mali: the urgent need for outdoor vector control strategies. Parasit Vectors, 2025. 18(1): p. 274.

Sarrassat, S., et al., Evaluation of Attractive Targeted Sugar Baits, a new outdoor vector control strategy against malaria: Results from a cluster randomised open-label parallel arm controlled trial in Southwestern Mali. J Infect, 2025. 91(1): p. 106524.

Mocchetti, A., et al., CRISPR/Cas9 knock-out of nAChR alpha6 confers resistance to spinosyns in Frankliniella occidentalis and is associated with a higher fitness cost than target-site mutation G275E. Pestic Biochem Physiol, 2025. 212: p. 106455.

Mavridis, K., et al., Identification and functional characterization of CYP3002B2, a cytochrome P450 associated with amitraz and flumethrin resistance in the major bee parasite Varroa destructor. Pestic Biochem Physiol, 2025. 210: p. 106364.

Mavridis, K., et al., Molecular surveillance of resistance mutations in invasive populations of Spodoptera frugiperda in Europe, for evidence-based pest control. Pest Manag Sci, 2025. 81(8): p. 4821-4830.

Kioulos, I., et al., Molecular genotyping of pyrethroid resistant mutations and their haplotypes in bed bug populations from Greece. Acta Trop, 2025. 265: p. 107624.

Haba, Y., et al., Ancient origin of an urban underground mosquito. bioRxiv, 2025.

Chen, Y., et al., dsRNAEngineer: a web-based tool of comprehensive dsRNA design for pest control. Trends Biotechnol, 2025. 43(4): p. 969-983.

Vandenhole, M., et al., Contrasting roles of cytochrome P450s in amitraz and chlorfenapyr resistance in the crop pest Tetranychus urticae. Insect Biochem Mol Biol, 2024. 164: p. 104039.

Tsakireli, D., et al., The cytochrome P450 subfamilies CYP392A and CYP392D are key players in acaricide metabolism in Tetranychusurticae. Pestic Biochem Physiol, 2024. 204: p. 106031.

Traore, M.M., et al., The efficacy of attractive targeted sugar baits in reducing malaria vector abundance in low-endemicity settings of northwest Mali. Malar J, 2024. 23(1): p. 319.

Superti-Furga, G., et al., EU-LIFE charter of independent life science research institutes. FEBS Lett, 2024. 598(7): p. 719-724.

Sakka, M.K., et al., Development, application and evaluation of three novel TaqMan qPCR assays for phosphine resistance monitoring in major stored product pests Tribolium castaneum and Rhyzopertha dominica. Pest Manag Sci, 2024. 80(2): p. 275-281.

Sakka, M.K., et al., High concentrations of piperonyl butoxide (PBO) enhance toxicity of S-methoprene against the lesser grain borer, Rhyzopertha dominica. Environ Sci Pollut Res Int, 2024. 31(39): p. 51344-51352.

Paronyan, L., et al., Molecular monitoring of insecticide resistance in major disease vectors in Armenia. Parasit Vectors, 2024. 17(1): p. 54.

Naalden, D., et al., Interaction of Whitefly Effector G4 with Tomato Proteins Impacts Whitefly Performance. Mol Plant Microbe Interact, 2024. 37(2): p. 98-111.

Kefi, M., et al., Insights into unique features of Drosophila CYP4G enzymes. Insect Biochem Mol Biol, 2024. 164: p. 104041.

Katsavou, E., et al., Characterisation of lepidopteran geranylgeranyl diphosphate synthase as a putative pesticide target. Insect Mol Biol, 2024. 33(2): p. 147-156.

Charamis, J., et al., Comparative Genomics Uncovers the Evolutionary Dynamics of Detoxification and Insecticide Target Genes Across 11 Phlebotomine Sand Flies. Genome Biol Evol, 2024. 16(9).

Balaska, S., et al., Development and application of species ID and insecticide resistance assays, for monitoring sand fly Leishmania vectors in the Mediterranean basin and in the Middle East. PLoS Negl Trop Dis, 2024. 18(12): p. e0012408.

Ateutchia-Ngouanet, S., et al., Monitoring Aedes populations for arboviruses, Wolbachia, insecticide resistance and its mechanisms in various agroecosystems in Benin. Acta Trop, 2024. 253: p. 107178.

Albaz, E., et al., Analysis of insecticide resistance and de novo transcriptome assembly of resistance associated genes in the European grapevine moth, Lobesia botrana (Lepidoptera: Tortricidae). Bull Entomol Res, 2024. 114(1): p. 88-98.

Woyessa, D., et al., Species composition, infection rate and detection of resistant alleles in Anopheles funestus (Diptera: Culicidae) from Lare, a malaria hotspot district of Ethiopia. Malar J, 2023. 22(1): p. 233.

Pym, A., et al., A single point mutation in the Bemisia tabaci cytochrome-P450 CYP6CM1 causes enhanced resistance to neonicotinoids. Insect Biochem Mol Biol, 2023. 156: p. 103934.

Panteleri, R., et al., Transgenic Drosophila to Functionally Validate Fall Armyworm ABCC2 Mutations Conferring Bt Resistance. Toxins (Basel), 2023. 15(6).

Njiru, C., et al., The complex II resistance mutation H258Y in succinate dehydrogenase subunit B causes fitness penalties associated with mitochondrial respiratory deficiency. Pest Manag Sci, 2023. 79(11): p. 4403-4413.

Meng, L.W., et al., Cuticular competing endogenous RNAs regulate insecticide penetration and resistance in a major agricultural pest. BMC Biol, 2023. 21(1): p. 187.

Mavridis, K., et al., Molecular diagnostics for monitoring insecticide resistance in the western flower thrips Frankliniella occidentalis. Pest Manag Sci, 2023. 79(4): p. 1615-1622.

Lu, X., et al., Increased metabolism in combination with the novel cytochrome b target-site mutation L258F confers cross-resistance between the Q(o) inhibitors acequinocyl and bifenazate in Tetranychus urticae. Pestic Biochem Physiol, 2023. 192: p. 105411.

Labbe, F., et al., Genomic analysis of two phlebotomine sand fly vectors of Leishmania from the New and Old World. PLoS Negl Trop Dis, 2023. 17(4): p. e0010862.

Kouadio, F.A., et al., Relationship between insecticide resistance profiles in Anopheles gambiae sensu lato and agricultural practices in Cote d'Ivoire. Parasit Vectors, 2023. 16(1): p. 270.

Kefi, M., et al., ABCH2 transporter mediates deltamethrin uptake and toxicity in the malaria vector Anopheles coluzzii. PLoS Pathog, 2023. 19(8): p. e1011226.

Kampouraki, A., et al., Functional characterization of cytochrome P450s associated with pyrethroid resistance in the olive fruit fly Bactrocera oleae. Pestic Biochem Physiol, 2023. 191: p. 105374.

Grant, C., et al., Overexpression of the UDP-glycosyltransferase UGT34A23 confers resistance to the diamide insecticide chlorantraniliprole in the tomato leafminer, Tuta absoluta. Insect Biochem Mol Biol, 2023. 159: p. 103983.

Darif, N., et al., Cell penetrating peptides are versatile tools for enhancing multimodal uptake into cells from pest insects. Pestic Biochem Physiol, 2023. 190: p. 105317.

Balaska, S., et al., Monitoring of Insecticide Resistance Mutations and Pathogen Circulation in Sand Flies from Emilia-Romagna, a Leishmaniasis Endemic Region of Northern Italy. Viruses, 2023. 15(1).

Xue, W., et al., The H92R substitution in PSST is a reliable diagnostic biomarker for predicting resistance to mitochondrial electron transport inhibitors of complex I in European populations of Tetranychus urticae. Pest Manag Sci, 2022. 78(8): p. 3644-3653.

Wipf, N.C., et al., Multi-insecticide resistant malaria vectors in the field remain susceptible to malathion, despite the presence of Ace1 point mutations. PLoS Genet, 2022. 18(2): p. e1009963.

Tadatsu, M., et al., A mutation in chitin synthase I associated with etoxazole resistance in the citrus red mite Panonychus citri (Acari: Tetranychidae) and its uneven geographical distribution in Japan. Pest Manag Sci, 2022. 78(10): p. 4028-4036.

Siden-Kiamos, I., et al., Dynamic interactions between the symbiont Candidatus Erwinia dacicola and its olive fruit fly host Bactrocera oleae. Insect Biochem Mol Biol, 2022. 146: p. 103793.

Samantsidis, G.R., et al., Functional characterization of putative ecdysone transporters in lepidopteran pests. Insect Biochem Mol Biol, 2022. 151: p. 103830.

Samantsidis, G.R., et al., Identification of Helicoverpa armigera promoters for biotechnological applications. Insect Biochem Mol Biol, 2022. 142: p. 103725.

Porretta, D., et al., Historical samples reveal a combined role of agriculture and public-health applications in vector resistance to insecticides. Pest Manag Sci, 2022. 78(4): p. 1567-1572.

Parsons, G.J.I., et al., A Practical Insecticide Resistance Monitoring Bioassay for Orally Ingested Dinotefuran in Anopheles Malaria Vectors. Insects, 2022. 13(4).

Papapostolou, K.M., et al., Over-expression in cis of the midgut P450 CYP392A16 contributes to abamectin resistance in Tetranychus urticae. Insect Biochem Mol Biol, 2022. 142: p. 103709.

Papadimitriou, F., et al., Flupyradifurone resistance in Myzus persicae populations from peach and tobacco in Greece. Pest Manag Sci, 2022. 78(1): p. 304-312.

Ngangue-Siewe, I.N., et al., Bendiocarb and Malathion Resistance in Two Major Malaria Vector Populations in Cameroon Is Associated with High Frequency of the G119S Mutation (Ace-1) and Overexpression of Detoxification Genes. Pathogens, 2022. 11(8).

Nauen, R., et al., The Role of Cytochrome P450s in Insect Toxicology and Resistance. Annu Rev Entomol, 2022. 67: p. 105-124.

Mavridis, K., et al., Multiple TaqMan qPCR and droplet digital PCR (ddPCR) diagnostics for pesticide resistance monitoring and management, in the major agricultural pest Tetranychus urticae. Pest Manag Sci, 2022. 78(1): p. 263-273.

Mavridis, K., et al., Next-generation molecular diagnostics (TaqMan qPCR and ddPCR) for monitoring insecticide resistance in Bemisia tabaci. Pest Manag Sci, 2022. 78(11): p. 4994-5001.

Malandrakis, A.A., et al., Fungicide resistance frequencies of Botrytis cinerea greenhouse isolates and molecular detection of a novel SDHI resistance mutation. Pestic Biochem Physiol, 2022. 183: p. 105058.

Luong, H.N.B., et al., Using tissue specific P450 expression in Drosophila melanogaster larvae to understand the spatial distribution of pesticide metabolism in feeding assays. Insect Mol Biol, 2022. 31(3): p. 369-376.

Lucchesi, V., et al., Cuticle Modifications and Over-Expression of the Chitin-Synthase Gene in Diflubenzuron-Resistant Phenotype. Insects, 2022. 13(12).

Katsavou, E., et al., Functionally characterized arthropod pest and pollinator cytochrome P450s associated with xenobiotic metabolism. Pestic Biochem Physiol, 2022. 181: p. 105005.

Kala-Chouakeu, N.A., et al., Pyrethroid Resistance Situation across Different Eco-Epidemiological Settings in Cameroon. Molecules, 2022. 27(19).

Ioannidis, P., et al., A spatiotemporal atlas of the lepidopteran pest Helicoverpa armigera midgut provides insights into nutrient processing and pH regulation. BMC Genomics, 2022. 23(1): p. 75.

Fotakis, E.A., et al., Mosquito population structure, pathogen surveillance and insecticide resistance monitoring in urban regions of Crete, Greece. PLoS Negl Trop Dis, 2022. 16(2): p. e0010186.

Denecke, S., et al., Characterization of a novel pesticide transporter and P-glycoprotein orthologues in Drosophila melanogaster. Proc Biol Sci, 2022. 289(1975): p. 20220625.

Xue, W., et al., Untangling a Gordian knot: the role of a GluCl3 I321T mutation in abamectin resistance in Tetranychus urticae. Pest Manag Sci, 2021. 77(4): p. 1581-1593.

Vorgia, E., et al., Functional characterization and transcriptomic profiling of a spheroid-forming midgut cell line from Helicoverpa zea (Lepidoptera: Noctuidae). Insect Biochem Mol Biol, 2021. 128: p. 103510.

Vlogiannitis, S., et al., Reduced proinsecticide activation by cytochrome P450 confers coumaphos resistance in the major bee parasite Varroa destructor. Proc Natl Acad Sci U S A, 2021. 118(6).

Vlogiannitis, S., et al., Pyrethroid target-site resistance mutations in populations of the honey bee parasite Varroa destructor (Acari: Varroidae) from Flanders, Belgium. Exp Appl Acarol, 2021. 85(2-4): p. 205-221.

Troczka, B.J., et al., Molecular innovations underlying resistance to nicotine and neonicotinoids in the aphid Myzus persicae. Pest Manag Sci, 2021. 77(12): p. 5311-5320.

Talipouo, A., et al., High insecticide resistance mediated by different mechanisms in Culex quinquefasciatus populations from the city of Yaounde, Cameroon. Sci Rep, 2021. 11(1): p. 7322.

Swevers, L., et al., Can the mammalian organoid technology be applied to the insect gut? Pest Manag Sci, 2021. 77(1): p. 55-63.

Singh, K.S., et al., Global patterns in genomic diversity underpinning the evolution of insecticide resistance in the aphid crop pest Myzus persicae. Commun Biol, 2021. 4(1): p. 847.

Sene, N.M., et al., Insecticide resistance status and mechanisms in Aedes aegypti populations from Senegal. PLoS Negl Trop Dis, 2021. 15(5): p. e0009393.

Sakka, M.K., et al., Transcriptomic analysis of s-methoprene resistance in the lesser grain borer, Rhyzopertha dominica, and evaluation of piperonyl butoxide as a resistance breaker. BMC Genomics, 2021. 22(1): p. 65.

Piameu, M., et al., Pyrethroid and Etofenprox Resistance in Anopheles gambiae and Anopheles coluzzii from Vegetable Farms in Yaounde, Cameroon: Dynamics, Intensity and Molecular Basis. Molecules, 2021. 26(18).

Papapostolou, K.M., et al., Identification and characterization of striking multiple-insecticide resistance in a Tetranychus urticae field population from Greece. Pest Manag Sci, 2021. 77(2): p. 666-676.

Nauen, R., C.T. Zimmer, and J. Vontas, Heterologous expression of insect P450 enzymes that metabolize xenobiotics. Curr Opin Insect Sci, 2021. 43: p. 78-84.

Moyes, C.L., et al., Correction: Contemporary status of insecticide resistance in the major Aedes vectors of arboviruses infecting humans. PLoS Negl Trop Dis, 2021. 15(1): p. e0009084.

Mavridis, K., K. Michaelidou, and J. Vontas, Highly sensitive droplet digital PCR-based diagnostics for the surveillance of malaria vector populations in low transmission and incipient resistance settings. Expert Rev Mol Diagn, 2021. 21(10): p. 1105-1114.

Mastrantonio, V., et al., Evolution of Adaptive Variation in the Mosquito Culex pipiens: Multiple Independent Origins of Insecticide Resistance Mutations. Insects, 2021. 12(8).

Luong, H.N.B., et al., Assessing the anti-resistance potential of public health vaporizer formulations and insecticide mixtures with pyrethroids using transgenic Drosophila lines. Parasit Vectors, 2021. 14(1): p. 495.

Livadaras, I., et al., Stably inherited transfer of the bacterial symbiont Candidatus Erwinia dacicola from wild olive fruit flies Bactrocera oleae to a laboratory strain. Bull Entomol Res, 2021. 111(3): p. 379-384.

Kefi, M., et al., Transcriptomic analysis of resistance and short-term induction response to pyrethroids, in Anopheles coluzzii legs. BMC Genomics, 2021. 22(1): p. 891.

Inak, E., et al., Population structure and insecticide resistance status of Tuta absoluta populations from Turkey. Pest Manag Sci, 2021. 77(10): p. 4741-4748.

Fotoukkiaii, S.M., et al., High-resolution genetic mapping reveals cis-regulatory and copy number variation in loci associated with cytochrome P450-mediated detoxification in a generalist arthropod pest. PLoS Genet, 2021. 17(6): p. e1009422.

Fotakis, E.A., et al., VectorMap-GR: A local scale operational management tool for entomological monitoring, to support vector control activities in Greece and the Mediterranean Basin. Curr Res Parasitol Vector Borne Dis, 2021. 1: p. 100053.

Djiappi-Tchamen, B., et al., Analyses of Insecticide Resistance Genes in Aedes aegypti and Aedes albopictus Mosquito Populations from Cameroon. Genes (Basel), 2021. 12(6).

Diarra, R.A., et al., Testing configurations of attractive toxic sugar bait (ATSB) stations in Mali, West Africa, for improving the control of malaria parasite transmission by vector mosquitoes and minimizing their effect on non-target insects. Malar J, 2021. 20(1): p. 184.

Denecke, S., et al., Comparative and functional genomics of the ABC transporter superfamily across arthropods. BMC Genomics, 2021. 22(1): p. 553.

Balaska, S., et al., Chemical control and insecticide resistance status of sand fly vectors worldwide. PLoS Negl Trop Dis, 2021. 15(8): p. e0009586.

Wei, P., et al., Overexpression of an alternative allele of carboxyl/choline esterase 4 (CCE04) of Tetranychus urticae is associated with high levels of resistance to the keto-enol acaricide spirodiclofen. Pest Manag Sci, 2020. 76(3): p. 1142-1153.

Vontas, J., E. Katsavou, and K. Mavridis, Cytochrome P450-based metabolic insecticide resistance in Anopheles and Aedes mosquito vectors: Muddying the waters. Pestic Biochem Physiol, 2020. 170: p. 104666.

Van Leeuwen, T., et al., Significance and interpretation of molecular diagnostics for insecticide resistance management of agricultural pests. Curr Opin Insect Sci, 2020. 39: p. 69-76.

Traore, M.M., et al., Large-scale field trial of attractive toxic sugar baits (ATSB) for the control of malaria vector mosquitoes in Mali, West Africa. Malar J, 2020. 19(1): p. 72.

Singh, K.S., et al., The genetic architecture of a host shift: An adaptive walk protected an aphid and its endosymbiont from plant chemical defenses. Sci Adv, 2020. 6(19): p. eaba1070.

Silva, R., et al., Monitoring and molecular profiling of contemporary insecticide resistance status of malaria vectors in Guinea-Bissau. Acta Trop, 2020. 206: p. 105440.

Samantsidis, G.R., et al., 'What I cannot create, I do not understand': functionally validated synergism of metabolic and target site insecticide resistance. Proc Biol Sci, 2020. 287(1927): p. 20200838.

Riga, M., et al., Co-Expression of a Homologous Cytochrome P450 Reductase Is Required for In Vivo Validation of the Tetranychus urticae CYP392A16-Based Abamectin Resistance in Drosophila. Insects, 2020. 11(12).

Riga, M., et al., Development of efficient RNAi in Nezara viridula for use in insecticide target discovery. Arch Insect Biochem Physiol, 2020. 103(3): p. e21650.

McLeman, A., et al., Fly-Tox: A panel of transgenic flies expressing pest and pollinator cytochrome P450s. Pestic Biochem Physiol, 2020. 169: p. 104674.

Lueke, B., et al., Identification and functional characterization of a novel acetyl-CoA carboxylase mutation associated with ketoenol resistance in Bemisia tabaci. Pestic Biochem Physiol, 2020. 166: p. 104583.

Koidou, V., et al., Efficient genome editing in the olive fruit fly, Bactrocera oleae. Insect Mol Biol, 2020. 29(4): p. 363-372.

Katsavou, E., et al., Identification and geographical distribution of pyrethroid resistance mutations in the poultry red mite Dermanyssus gallinae. Pest Manag Sci, 2020. 76(1): p. 125-133.

Ingham, V.A., et al., A sensory appendage protein protects malaria vectors from pyrethroids. Nature, 2020. 577(7790): p. 376-380.

Guz, N., et al., Detection of diflubenzuron and pyrethroid resistance mutations in Culex pipiens from Mugla, Turkey. Acta Trop, 2020. 203: p. 105294.

Fotakis, E.A., et al., Identification and detection of a novel point mutation in the Chitin Synthase gene of Culex pipiens associated with diflubenzuron resistance. PLoS Negl Trop Dis, 2020. 14(5): p. e0008284.

Fotakis, E.A., et al., Population dynamics, pathogen detection and insecticide resistance of mosquito and sand fly in refugee camps, Greece. Infect Dis Poverty, 2020. 9(1): p. 30.

Douris, V., et al., Using CRISPR/Cas9 genome modification to understand the genetic basis of insecticide resistance: Drosophila and beyond. Pestic Biochem Physiol, 2020. 167: p. 104595.

Dermauw, W., et al., Targeted mutagenesis using CRISPR-Cas9 in the chelicerate herbivore Tetranychus urticae. Insect Biochem Mol Biol, 2020. 120: p. 103347.

Denecke, S.M., et al., The Identification and Evolutionary Trends of the Solute Carrier Superfamily in Arthropods. Genome Biol Evol, 2020. 12(8): p. 1429-1439.

Denecke, S., et al., A transcriptomic and proteomic atlas of expression in the Nezara viridula (Heteroptera: Pentatomidae) midgut suggests the compartmentalization of xenobiotic metabolism and nutrient digestion. BMC Genomics, 2020. 21(1): p. 129.

Blow, F., et al., Functional Genomics of a Symbiotic Community: Shared Traits in the Olive Fruit Fly Gut Microbiota. Genome Biol Evol, 2020. 12(2): p. 3778-3791.

Balaska, S., et al., Bioassay and molecular monitoring of insecticide resistance status in Aedes albopictus populations from Greece, to support evidence-based vector control. Parasit Vectors, 2020. 13(1): p. 328.

Alavijeh, E.S., et al., Molecular and genetic analysis of resistance to METI-I acaricides in Iranian populations of the citrus red mite Panonychus citri. Pestic Biochem Physiol, 2020. 164: p. 73-84.